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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUSP3 All Species: 9.09
Human Site: S17 Identified Species: 16.67
UniProt: P51452 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.42
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51452 NP_004081.1 185 20478 S17 Q D L N D L L S D G S G C Y S
Chimpanzee Pan troglodytes P0C594 220 25358 E42 T P G A F E L E R L F W K G S
Rhesus Macaque Macaca mulatta XP_001113728 144 16144 G14 I P K L Q K L G I T H V L N A
Dog Lupus familis XP_537624 228 25143 S60 Q D L N D L L S D G S G C Y S
Cat Felis silvestris
Mouse Mus musculus Q9D7X3 185 20454 S17 Q D L N D L L S D G S G C Y S
Rat Rattus norvegicus P0C595 215 24055 E41 T P G A F E L E R L F W K G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506876 252 28589 D85 Y Q T P T L A D L Q R L L L E
Chicken Gallus gallus P0C597 214 24304 E32 Y C T P G A F E L E R L F W K
Frog Xenopus laevis Q4KL92 209 23732 E33 T P G A F E L E R L F W H G A
Zebra Danio Brachydanio rerio Q29RA3 189 21985 Q21 T P S C Y E L Q K H F T H G G
Tiger Blowfish Takifugu rubipres P0C599 210 23683 Q34 P G T L D L E Q L F W S G P G
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624869 211 24264 D45 P G F D P N R D D V E Y Y R I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791989 192 21775 K19 D E L E N V M K K G S I V I A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.7 77.8 79.3 N.A. 92.9 39.5 N.A. 33.3 34.5 36.3 40.2 42.8 N.A. 40.7 N.A. 45.8
Protein Similarity: 100 55.4 77.8 79.8 N.A. 96.2 56.7 N.A. 47.2 51.4 54.5 57.1 57.6 N.A. 58.2 N.A. 64
P-Site Identity: 100 13.3 6.6 100 N.A. 100 13.3 N.A. 6.6 0 6.6 6.6 13.3 N.A. 6.6 N.A. 20
P-Site Similarity: 100 13.3 13.3 100 N.A. 100 13.3 N.A. 6.6 6.6 13.3 6.6 13.3 N.A. 13.3 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 24 0 8 8 0 0 0 0 0 0 0 24 % A
% Cys: 0 8 0 8 0 0 0 0 0 0 0 0 24 0 0 % C
% Asp: 8 24 0 8 31 0 0 16 31 0 0 0 0 0 0 % D
% Glu: 0 8 0 8 0 31 8 31 0 8 8 0 0 0 8 % E
% Phe: 0 0 8 0 24 0 8 0 0 8 31 0 8 0 0 % F
% Gly: 0 16 24 0 8 0 0 8 0 31 0 24 8 31 16 % G
% His: 0 0 0 0 0 0 0 0 0 8 8 0 16 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 8 0 0 8 0 8 8 % I
% Lys: 0 0 8 0 0 8 0 8 16 0 0 0 16 0 8 % K
% Leu: 0 0 31 16 0 39 62 0 24 24 0 16 16 8 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 24 8 8 0 0 0 0 0 0 0 8 0 % N
% Pro: 16 39 0 16 8 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 24 8 0 0 8 0 0 16 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 24 0 16 0 0 8 0 % R
% Ser: 0 0 8 0 0 0 0 24 0 0 31 8 0 0 39 % S
% Thr: 31 0 24 0 8 0 0 0 0 8 0 8 0 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 8 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 24 0 8 0 % W
% Tyr: 16 0 0 0 8 0 0 0 0 0 0 8 8 24 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _